Clustering tendency in the protein fold space
نویسندگان
چکیده
منابع مشابه
Clustering tendency in the protein fold space
Several non-redundant ensembles of protein three-dimensional structures were analyzed in order to estimate their natural clustering tendency by means of the Cox-Lewis coefficient. It was observed that, despite proteins tend to aggregate into different and well separated groups, some overlap between different clusters occurs. This suggests that classifications bases only on structural data canno...
متن کاملFlexible Clustering by Tendency in High Dimensional Space
Clustering is the process of grouping a set of objects into classes of similar objects. Until recently, the concept of similarity is based on distances, e.g Euclidean distance and cosine distance. Our previous work on δ-cluster and δ-pCluster designed new similarity models to capture subspace coherency exhibited in data and focused on shifting patterns or scaling patterns. Along the same genera...
متن کاملOP-Cluster: Clustering by Tendency in High Dimensional Space
Clustering is the process of grouping a set of objects into classes of similar objects. Because of unknownness of the hidden patterns in the data sets, the definition of similarity is very subtle. Until recently, similarity measures are typically based on distances, e.g Euclidean distance and cosine distance. In this paper, we propose a flexible yet powerful clustering model, namely OP-Cluster ...
متن کاملTouring protein fold space with Dali/FSSP
The FSSP database and its new supplement, the Dali Domain Dictionary, present a continuously updated classification of all known 3D protein structures. The classification is derived using an automatic structure alignment program (Dali) for the all-against-all comparison of structures in the Protein Data Bank. From the resulting enumeration of structural neighbours (which form a surprisingly con...
متن کاملAn alternative view of protein fold space.
Comparing and subsequently classifying protein structures information has received significant attention concurrent with the increase in the number of experimentally derived 3-dimensional structures. Classification schemes have focused on biological function found within protein domains and on structure classification based on topology. Here an alternative view is presented that groups substruc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioinformation
سال: 2010
ISSN: 0973-8894,0973-2063
DOI: 10.6026/97320630004347